Overview of Q fever

 Q fever is a zoonotic( infectious disease that can bet ransmitted from non-human animals, both wild and domestic, to humans or from humans to non-human animals (the latter is sometimes called reverse zoonosis)) disease caused by Coxiella burnetii, a species of bacteria that is distributed globally.  In 1999, Q fever became a notifiable disease in the United States but reporting is not required in many other countries. Because the disease is underreported, scientists cannot reliably assess how many cases of Q fever have actually occurred worldwide.  Many human infections are inapparent.

It was first described by Edward Holbrook Derrick in abattoir workers in Brisbane, Queensland, Australia. The "Q" stands for "query" and was applied at a time when the causative agent was unknown; it was chosen over suggestions of "abattoir fever" and "Queensland rickettsial fever", to avoid directing negative connotations at either the cattle industry or the state of Queensland.

The pathogen of Q fever was discovered in 1937, when Frank Macfarlane Burnet and Mavis Freeman isolated the bacterium from one of Derrick’s patients. It was originally identified as a species of Rickettsia. H.R. Cox and Davis isolated it from ticks in Montana, USAin 1938.It is a zoonotic disease whose most common animal reservoirs are cattle, sheep and goats. Coxiella burnetii is no longer regarded as closely related toRickettsiae but as similar to Legionella and Francisella and is a proteobacterium.